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when a single oral 30 mg dose of paroxetine hydrochloride was administered at phenobarbital steady state 100 mg once daily for 14 days , paroxetine auc and t were reduced by an average of 25 and 38 , respectively compared to paroxetine administered alone.

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long-term maintenance effects of paroxetine tablets in panic disorder were demonstrated in an extension to study 1.

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the most commonly observed adverse events associated with the use of paroxetine incidence of 5 or greater and incidence for paxil at least twice that for placebo, derived from table 4 were asthenia, sweating, nausea, dry mouth, diarrhea, decreased appetite, somnolence, libido decreased, abnormal ejaculation, female genital disorders, and impotence.

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patients were dosed in a range of 10 to 60 mg day in the clinical trials demonstrating the effectiveness of paroxetine.
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  • In this trial, patients assigned to paroxetine showed a lower relapse rate compared to patients on placebo see clinical pharma ...

  • Although the efficacy of paroxetine hydrochloride beyond 12 weeks of dosing has not been demonstrated in controlled clinical t ...

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